Intronic RNAscope probes enable precise identification of cardiomyocyte nuclei and cell cycle activity

Abstract Cardiac regeneration studies have been plagued by technical challenges in unequivocally identifying cardiomyocyte (CM) nuclei in cardiac sections, crucial for accurate identification of cycling CMs. The use of antibodies to sarcomeric proteins is error-prone, the CM specificity of common nu...

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Bibliographic Details
Main Authors: Zhe Yu, Sen Zhang, Julius Bogomolovas, Ju Chen, Sylvia M. Evans
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08012-z
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