Characterization of spreading depolarizations in swine following superior sagittal sinus occlusion: a novel gyrencephalic model study

Characterization of spreading depolarizations in swine following superior sagittal sinus occlusion: a novel gyrencephalic model study

Abstract Cerebral sinus thrombosis, which constitutes a small percentage of all strokes, usually affects young individuals and can lead to venous stroke. Ischemic and hemorrhagic Stroke are associated with Spreading Depolarization (SD) waves in brain tissue, which propagate through the affected area...

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Main Authors: Renan Sanchez-Porras, Francisco L. Ramírez-Cuapio, Mildred A. Gutiérrez-Herrera, Ángel Alberto Puig-Lagunes, Pablo Albiña-Palmarola, Juan M. López-Navarro, Marcos Alejandro Suárez-Gutiérrez, Roberto Díaz-Peregrino, Diego A. Sandoval-Lopez, Gregor Fischer, Farzam Vazifehdan, Johannes Woitzik, Edgar Santos
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Thrombosis Journal
Subjects:
Cerebral venous occlusion
Electrocorticography (ECoG)
Intrinsic optical signal imaging (IOS)
Laser speckle contrast and oxygen imaging (LSCI)
Spreading depolarizations (SDs)
Superior sagittal sinus (SSS)
Online Access:https://doi.org/10.1186/s12959-025-00689-w
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https://doi.org/10.1186/s12959-025-00689-w

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