Prognostic role of angiotensin-II receptor type 1 and endothelin-1 receptor type A agonistic autoantibodies in patients with acute myocardial infarction

Prognostic role of angiotensin-II receptor type 1 and endothelin-1 receptor type A agonistic autoantibodies in patients with acute myocardial infarction

BackgroundFunctional autoantibodies against angiotensin II type 1 (AT1R-AAs) and endothelin-1 type A (ETAR-AAs) receptors are associated with microvascular obstruction and myocardial remodeling after ST-elevation myocardial infarction (STEMI). However, their role in the long-term prognosis after STE...

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Main Authors: Francesco Tona, Giovanni Civieri, Marta Vadori, Giulia Masiero, Laura Iop, Martina Perazzolo Marra, Annagrazia Cecere, Marika Martini, Donatella Tansella, Giacomo Bernava, Benedetta Schiavon, Loira Leoni, Emanuele Cozzi, Sabino Iliceto
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
autoimmunity
no-reflow
coronary microcirculation
G protein coupled receptors
acute coronary syndrome
adverse prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1515693/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1515693/full

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