Effects of Intranasal dexmedetomidine and esketamine for premedication on postoperative pain after tonsillectomy and adenoidectomy in children: a randomized clinical trial

Abstract Background Postoperative acute pain is a common issue in children after surgery. Our study aimed to investigate whether preoperative use of a dexmedetomidine–esketamine combination could reduce postoperative pain in children undergoing tonsillectomy and adenoidectomy and reduce side effects...

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Bibliographic Details
Main Authors: Jun-wei Qi, Chuang Li, Xin-yuan Qiu, Xin-ge Wen, Hua Yin, Qing-ling Meng, Li Li, Qian Zhang, Yue-ying Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Anesthesiology
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Online Access:https://doi.org/10.1186/s12871-025-03203-x
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