Effective gene trapping mediated by Sleeping Beauty transposon.

Gene trapping is a high-throughput approach to elucidate gene functions by disrupting and recapitulating expression of genes in a target genome. A number of transposon-based gene-trapping systems are developed for mutagenesis in cells and model organisms, but there is still much room for the improve...

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Bibliographic Details
Main Authors: Guili Song, Qing Li, Yong Long, Qilin Gu, Perry B Hackett, Zongbin Cui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0044123&type=printable
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