Harnessing Actinobacteria secondary metabolites for tuberculosis drug discovery: Historical trends, current status and future outlooks

Harnessing Actinobacteria secondary metabolites for tuberculosis drug discovery: Historical trends, current status and future outlooks

Abstract Tuberculosis (TB) is a leading infectious disease killer and one of the major causes of deaths worldwide. Although TB is a curable and preventable disease, in 2023, approximately 10.8 million people fell ill with TB and there were an estimated 1.25 million of deaths worldwide. Despite some...

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Main Authors: Luana Layse Câmara de Almeida, Sayoane Pessoa Fernandes, Genil Dantas de Oliveira, Marcelly da Silveira Silva, Thalisson Amorim de Souza, Valnês S. Rodrigues-Junior, Samuel Paulo Cibulski
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:Natural Products and Bioprospecting
Subjects:
Antimycobacterial activity
Natural products
Actinomycete
Secondary metabolites
Antibiotics
Online Access:https://doi.org/10.1007/s13659-025-00533-8
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https://doi.org/10.1007/s13659-025-00533-8

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