ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease

ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease

Abstract Chronic obstructive pulmonary disease (COPD) is a characteristic chronic airway inflammatory disease that worsens over time, however, there are currently limited clinical therapeutics to suspend its progression. Circular RNAs (circRNAs), which have emerged as functional regulators in variou...

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Main Authors: Ting‐Ting Chen, Yuan‐Yuan Wei, Jia‐Ying Kang, Da‐Wei Zhang, Jing‐Jing Ye, Xi‐Shi Sun, Mei Hong, Wen‐Ting Zhang, Hui‐Mei Wu, Zhen‐Xing Ding, Guang‐He Fei
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
autophagy
chronic obstructive pulmonary disease
CircCANX
CircRNA biogenesis
nonsense‐mediated mRNA decay
stress granule
Online Access:https://doi.org/10.1002/advs.202414211
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https://doi.org/10.1002/advs.202414211

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