Assessing the genetic profile of cytochrome P450 and glutathione S-transferases of patients diagnosed with acute myeloid leukemia

Assessing the genetic profile of cytochrome P450 and glutathione S-transferases of patients diagnosed with acute myeloid leukemia

Objective: This study aimed to determine the frequency of genetic alterations as deletions and duplications in cytochrome P450 (CYP450) and glutathione S-transferases (GST) genes, as well as to investigate whether there is a relationship between these alterations and neutrophilic hematologic recover...

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Main Authors: Gilmar de Andrade França, Luciana Nardinelli, Ricardo Rodrigues Giorgi, Thiago Pagliarini, Otávio César Carvalho Guimarães Baiocchi, Elvira Deolinda Rodrigues Pereira Velloso, Wellington Fernandes da Silva Jr, Eduardo Magalhães Rego, Israel Bendit
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Hematology, Transfusion and Cell Therapy
Subjects:
Pharmacogenomics
Acute myeloid leukemia
Polymorphism
Glutathione s-transferase
Cytochrome P450
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137925000276
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