A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium berghei

A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium berghei

Mitosis in eukaryotes involves reorganisation of the nuclear envelope (NE) and microtubule-organising centres (MTOCs). During male gametogenesis in Plasmodium, the causative agent of malaria, mitosis is exceptionally rapid and highly divergent. Within 8 min, the haploid male gametocyte genome underg...

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Main Authors: Mohammad Zeeshan, Igor Blatov, Ryuji Yanase, David JP Ferguson, Sarah L Pashley, Zeinab Chahine, Yoshiki Yamaryo-Botté, Akancha Mishra, Baptiste Marche, Suhani Bhanvadia, Molly Hair, Sagar Batra, Robert Markus, Declan Brady, Andrew R Bottrill, Sue Vaughan, Cyrille Y Botté, Karine G Le Roch, Anthony A Holder, Eelco Tromer, Rita Tewari
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
malaria
gametogenesis
P. berghei
transmission
nuclear enevelope
basal body
Online Access:https://elifesciences.org/articles/106537
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https://elifesciences.org/articles/106537

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