Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice
AAV-PHP.eB is an artificial adeno-associated virus (AAV) that crosses the blood–brain barrier and targets neurons more efficiently than other AAVs when administered systematically. While AAV-PHP.eB has been used in various disease models, its cellular tropism in cerebrovascular diseases remains uncl...
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| Main Authors: | Rubing Shi, Jing Ye, Ze Liu, Cheng Wang, Shengju Wu, Hui Shen, Qian Suo, Wanlu Li, Xiaosong He, Zhijun Zhang, Yaohui Tang, Guo-Yuan Yang, Yongting Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2026-02-01
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| Series: | Neural Regeneration Research |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/NRR.NRR-D-23-01802 |
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