Metabolic effects of high-dose glucocorticoid following out-of-hospital cardiac arrest

Metabolic effects of high-dose glucocorticoid following out-of-hospital cardiac arrest

Abstract Background and aim Patients resuscitated after out-of-hospital cardiac arrest (OHCA) face high morbidity and mortality rates, primarily due to ischemia–reperfusion injury, a complex metabolic disorder that triggers a significant systemic inflammatory response. Glucocorticoids mitigate infla...

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Bibliographic Details
Main Authors: Rasmus Paulin Beske, Laust Emil Roelsgaard Obling, Martin Abild Stengaard Meyer, Jacob Eifer Møller, Jesper Kjaergaard, Pär Ingemar Johansson, Christian Hassager
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Intensive Care Medicine Experimental
Subjects:
Cardiac arrest
Glucocorticoid
Methylprednisolone
Metabolomics
Inflammation
Online Access:https://doi.org/10.1186/s40635-025-00754-8
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https://doi.org/10.1186/s40635-025-00754-8

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