Spray-Dried Polymeric Microspheres for Lipophilic Drugs: Formulation Design, Physicochemical Characterization, and In Vitro Release Evaluation

Spray-Dried Polymeric Microspheres for Lipophilic Drugs: Formulation Design, Physicochemical Characterization, and In Vitro Release Evaluation

<b>Background/Objectives</b>: The formulation of microspheres for lipophilic drugs using aqueous methods, such as spray drying, faces significant challenges. The main objective of this study was to evaluate the effect of the process parameters and polymer selection on the production of m...

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Main Authors: Felipe Nataren-Rodríguez, Jorge Pacheco-Molina, Sandra Leticia Gracia-Vásquez, Isaías Balderas-Rentería, Mónica A. Ramírez-Cabrera, Eder Arredondo-Espinoza, Karla J. Santamaría, Patricia González-Barranco
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceuticals
Subjects:
Eudragit
guar gum
hydroxypropyl methylcellulose
inulin
lipophilic drugs
microsphere
Online Access:https://www.mdpi.com/1424-8247/18/7/1020
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