Klotho modulation by tempol: a potential therapeutic axis in sepsis
Abstract Background Sepsis is characterized by massive inflammatory and oxidative stress responses. The imbalance between oxidant and antioxidant activities during sepsis contributes to hyperinflammation, oxidation, endothelin system activation, and apoptosis, key elements of multiorgan failure. The...
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| Main Authors: | Alaa Al-kadi, Aliaa F. Anter, Remon Roshdy Rofaeil, Mohamed M. Sayed-Ahmed, Sara Mohamed Naguib Abdel Hafez, Al-Shaimaa F. Ahmed |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-025-04738-0 |
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