Targeting CD96 overcomes PD-1 blockade resistance by enhancing CD8+ TIL function in cervical cancer

Background Novel therapies are needed to treat recurrent and advanced cervical cancer (CC), as their prognosis remains very poor. Although therapies targeting the programmed cell death protein 1 (PD-1) pathway have been approved for CC, a large subset of patients exhibit innate resistance. Using che...

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Bibliographic Details
Main Authors: Meng Zhang, Guiling Li, Jing Peng, Keqin Hua, Yumeng Wang, Congwen Wang, Junjun Qiu, Xinyu Qu, Chong Lu, Mingxing Zhang, Xingling Qi
Format: Article
Language:English
Published: BMJ Publishing Group 2022-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/3/e003667.full
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