Revisiting insulin-stimulated hydrogen peroxide dynamics reveals a cytosolic reductive shift in skeletal muscle

Revisiting insulin-stimulated hydrogen peroxide dynamics reveals a cytosolic reductive shift in skeletal muscle

The intracellular redox state is crucial for insulin responses in peripheral tissues. Despite the longstanding belief that insulin signaling increases hydrogen peroxide (H2O2) production leading to reversible oxidation of cysteine thiols, evidence is inconsistent and rarely involves human tissues. I...

Full description

Saved in:
Bibliographic Details
Main Authors: Carlos Henríquez-Olguín, Samantha Gallero, Anita Reddy, Kaspar W. Persson, Farina L. Schlabs, Christian T. Voldstedlund, Gintare Valentinaviciute, Roberto Meneses-Valdés, Casper M. Sigvardsen, Bente Kiens, Edward T. Chouchani, Erik A. Richter, Thomas E. Jensen
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172500120X
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S221323172500120X

Similar Items