The Mitochondrial Disulfide Relay System: Roles in Oxidative Protein Folding and Beyond

Disulfide bond formation drives protein import of most proteins of the mitochondrial intermembrane space (IMS). The main components of this disulfide relay machinery are the oxidoreductase Mia40 and the sulfhydryl oxidase Erv1/ALR. Their precise functions have been elucidated in molecular detail for...

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Bibliographic Details
Main Authors: Manuel Fischer, Jan Riemer
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2013/742923
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