SCN10A gene polymorphism is associated with pain sensitivity and postoperative analgesic effects in patients undergoing gynecological laparoscopy

Abstract Background Postoperative pain intensity is influenced by various factors, including genetic variations. The SCN10A gene encodes the Nav1.8 sodium channel protein, which is crucial for pain signal transmission in peripheral sensory neurons. Objectives This study aims to investigate the relat...

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Bibliographic Details
Main Authors: Yang Gao, Jing Li, Lin Gan, Meng Cai, Xiaofeng Lei, Jin Yu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02284-1
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