Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells.

Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells.

Despite the widespread application of RNA interference (RNAi) as a research tool for diverse purposes, the key step of strand selection of siRNAs during the formation of RNA-induced silencing complex (RISC) remains poorly understood. Here, using siRNAs targeted to the complementary region of Survivi...

Full description

Saved in:
Bibliographic Details
Main Authors: Jun-Xia Wei, Jie Yang, Ji-Feng Sun, Lin-Tao Jia, Yong Zhang, Hui-Zhong Zhang, Xia Li, Yan-Ling Meng, Li-Bo Yao, An-Gang Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005382&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005382&type=printable

Similar Items