Neurodegeneration models in Parkinson’s disease: cellular and molecular paths to neuron death

Neurodegeneration models in Parkinson’s disease: cellular and molecular paths to neuron death

Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects dopaminergic neurons in the substantia nigra pars compacta. It is a complex disease that is strongly influenced by environmental and genetic factors. While the exact causes of PD are not well understood, resea...

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Main Authors: Diana D. Álvarez-Luquín, Rubén R. González-Fernández, Martin E. Torres-Velasco, Eduardo Ichikawa-Escamilla, Asiel Arce-Sillas, Eduardo Martínez-Martínez, Clara L. Miranda-Narvaez, Juan F. Rodríguez-Ramírez, Laura Adalid-Peralta
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Behavioral and Brain Functions
Subjects:
Neurodegeneration
Parkinson disease
Dopaminergic neuron
Neuronal death
Molecular mechanism
Online Access:https://doi.org/10.1186/s12993-025-00279-w
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https://doi.org/10.1186/s12993-025-00279-w

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