Serum Levels of N<sup>ε</sup>-(Carboxymethyl)-Lysine in Chronic Kidney Disease and Type 2 Diabetes Mellitus

Serum Levels of N<sup>ε</sup>-(Carboxymethyl)-Lysine in Chronic Kidney Disease and Type 2 Diabetes Mellitus

<b>Background</b>: N<sup>ε</sup>-(carboxymethyl)-lysine (CML) is formed in the human body by non-enzymatically driven reactions including glycation, oxidation, and lipoxidation. CML is a ubiquitous product of normal physiology, but its levels are increased under disease condi...

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Main Authors: Rositsa Tsekovska, Evan Gatev, Roumyana Mironova, Simona Kerezieva, Siyana Ilieva, Teodora Ilieva, Bilyana Vasileva, Toshimitsu Niwa, Daniela Popova, Vasil Vasilev
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
advanced glycation end products
glycoxidation
N<sup>ε</sup>-(carboxymethyl)-lysine
chronic kidney disease
diabetes mellitus
Online Access:https://www.mdpi.com/2227-9059/13/7/1672
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