Characterization of Ketoprofen/Methyl-β-Cyclodextrin Complexes Prepared Using Supercritical Carbon Dioxide
Complexes of methyl-β-cyclodextrin and ketoprofen, a crystalline anti-inflammatory drug with poor water solubility, have been prepared for the first time in the presence of supercritical CO2 at 40°C and 20 MPa. The supercritical treatment allows these pharmaceutical formulations to be prepared witho...
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Main Authors: | Mauro Banchero, Silvia Ronchetti, Luigi Manna |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2013/583952 |
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