Sea Squirt-Derived Peptide WLP Mitigates OKA-Induced Alzheimer’s Disease-like Phenotypes in Human Cerebral Organoid

Sea Squirt-Derived Peptide WLP Mitigates OKA-Induced Alzheimer’s Disease-like Phenotypes in Human Cerebral Organoid

Alzheimer’s disease (AD), a prevalent neurodegenerative disorder in the elderly, poses significant humanistic and economic burdens worldwide. Previously, we identified Trp-Leu-Pro (WLP), a novel antioxidant peptide derived from the sea squirt (<i>Halocynthia roretzi</i>); however, its ef...

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Bibliographic Details
Main Authors: Qiqi Chen, Zhiqiu Wang, Wei Guo, Aiqin Xue, Guohui Bian, Xinhua Guo, Shiya Lu, Pinli Zeng, Hao Li, Xizhi Zhu, Yan Huang, Xiaobo Cen, Qian Bu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antioxidants
Subjects:
food-derived peptide
Alzheimer’s disease
okadaic acid
cerebral organoids
Online Access:https://www.mdpi.com/2076-3921/14/5/553
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