3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

Abstract A central focus of bone tissue engineering is the construction of vascular systems, which provide nutrients for cell survival, remove metabolic waste, and accelerate tissue regeneration. Platelet‐derived growth factor‐BB (PDGFB) has the ability to stimulate both vascularization and bone reg...

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Bibliographic Details
Main Authors: Jiahua Duan, Gaofei Qian, Huikang Zhang, Feifan Wang, Qiang Tian, Dong Lei, Jianning Zhao
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
biomimetic vascular scaffold
bone regeneration
fusion protein
heparan sulfate
vascularization
Online Access:https://doi.org/10.1002/advs.202414362
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https://doi.org/10.1002/advs.202414362

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