In situ implantation of type II collagen-based double-layer scaffolds for Articular Osteochondral Regeneration comprising hyaline cartilage and vascularized subchondral bones

In situ implantation of type II collagen-based double-layer scaffolds for Articular Osteochondral Regeneration comprising hyaline cartilage and vascularized subchondral bones

The articular osteochondral injury involves the repair of hyaline cartilage, subchondral bone plate, and cancellous bone. Due to the weak regeneration ability of chondrocytes and the complex structure of the bone-cartilage junction, there is currently no excellent repair method. The challenge of hya...

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Bibliographic Details
Main Authors: Zhen Zhang, Ye Huang, Xu Hu, Yulei Mu, Huiqun Zhou, Liang Ma, Bangheng Liu, Hang Yao, Xieyuan Jiang, Dong-An Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-08-01
Series:Bioactive Materials
Subjects:
Osteochondral
Hyaline cartilage regeneration
Endochondral ossification
Type II collagen
Polydopamine
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25001525
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