Balanced CoQ6 biosynthesis is required for lifespan and mitophagy in yeast

Balanced CoQ6 biosynthesis is required for lifespan and mitophagy in yeast

Coenzyme Q is an essential lipid with redox capacity that is present in all organisms. In yeast its biosynthesis depends on a multiprotein complex in which Coq7 protein has both catalytic and regulatory functions. Coq7 modulates CoQ6 levels through a phosphorylation cycle, where dephosphorylation of...

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Bibliographic Details
Main Authors: I. González-Mariscal, A. Martín-Montalvo, C. Ojeda-González, A. Rodríguez-Eguren, P. Gutiérrez-Ríos, P. Navas, C. Santos-Ocaña
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-02-01
Series:Microbial Cell
Subjects:
coenzyme Q6
regulation
mitochondria
yeast
mitophagy
chronological life span
Online Access:http://microbialcell.com/researcharticles/balanced-coq6-biosynthesis-is-required-for-lifespan-and-mitophagy-in-yeast/
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http://microbialcell.com/researcharticles/balanced-coq6-biosynthesis-is-required-for-lifespan-and-mitophagy-in-yeast/

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