Analysis of the features of planning bioequivalence studies with adaptive design for drug products analogous to endogenous compounds ademetionine

Introduction. Adaptive design in clinical bioequivalence studies offers a more flexible approach, allowing for modifications to protocols during the trial based on accumulated data. This is particularly relevant for drugs that are analogs of endogenous compounds, such as ademetionine, due to the pre...

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Bibliographic Details
Main Author: N. N. Eremenko
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2025-06-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/2056
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