脂联素与糖尿病肾脏疾病的关系及其效应机制的研究进展
<正>糖尿病肾脏疾病（diabetic kidney disease,DKD）是糖尿病微血管并发症之一,病理变化表现为肾小球及肾小管肥大、肾小球及肾小管基膜增厚和肾小球硬化等,其发病机制复杂,炎症、氧化应激、生化代谢紊乱、内皮损伤、蛋白尿、遗传易感性等机制均参与其中。脂联素是脂肪组织中含量最丰富的转录产物之一,自其首次被发现以来,Yamauchi等<sup>[1]</sup>首先用分子克隆技术确定了两种脂联素受体,即脂联素受体1（AdipoR<sub>1</sub>）和脂联素受体2（AdipoR<sub>2</sub...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2016-01-01
|
| Series: | Linchuang shenzangbing zazhi |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57919531&Fpath=home&index=0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|