The SRG rat as a novel host for an orthotopic patient-derived xenograft model of breast cancer brain metastasis
Abstract Patient-derived xenograft (PDX) models are essential for understanding the pathophysiology and developing treatment strategies for breast cancer brain metastasis (BCBM). While immunodeficient mouse models allow for human BCBM growth, their small size limits host survival, neurological imagi...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-06090-x |
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