L. extract Attenuates Angiogenesis Through HIF-1α and WNT Mediated Blockage of VEGF/Angiopoietin Axis

L. extract Attenuates Angiogenesis Through HIF-1α and WNT Mediated Blockage of VEGF/Angiopoietin Axis

Objectives The current study investigated angiogenesis-arresting attributes of Mesua ferrea oleo-gum resin extract and its underlying molecular mechanisms. Methods Series of in vitro , ex vivo and in vivo models were used to assess anti-angiogenic properties. Results MTT cell viability experiments s...

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Main Authors: Fengwei Zhang, Mohamed Farouk Elsadek, Shafqat Rasul Chaudhry, Nojood Altwaijry, Shamsuddin Sultan Khan, Seyedeh Fatemeh Jafari, Aman Shah Abdul Majid, Chern Ein Oon, Amin Malik Shah Abdul Majid, Thomas Efferth, Muhammad Asif
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/15593258251367613
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https://doi.org/10.1177/15593258251367613

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