Optimising dynamic treatment regimens using sequential multiple assignment randomised trials data with missing data

Optimising dynamic treatment regimens using sequential multiple assignment randomised trials data with missing data

Abstract Dynamic treatment regimens are commonly used for patients with chronic or progressive medical conditions. Sequential multiple assignment randomised trials (SMARTs) are studies used to optimise dynamic treatment regimens by repeatedly randomising participants to treatments. Q-learning, a sta...

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Bibliographic Details
Main Authors: Jessica Xu, Anurika P. De Silva, Katherine J. Lee, Robert K. Mahar, Julie A. Simpson
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medical Research Methodology
Subjects:
Sequential multiple assignment randomised trials
Missing data
Q-learning
Multiple imputation
Online Access:https://doi.org/10.1186/s12874-025-02595-1
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https://doi.org/10.1186/s12874-025-02595-1

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