Variable orthogonality of serine integrase interactions within the ϕC31 family

Variable orthogonality of serine integrase interactions within the ϕC31 family

Abstract Serine integrases are phage- (or mobile element-) encoded enzymes that catalyse site-specific recombination reactions between a short DNA sequence on the phage genome (attP) and a corresponding host genome sequence (attB), thereby integrating the phage DNA into the host genome. Each integra...

Full description

Saved in:
Bibliographic Details
Main Authors: Alasdair I. MacDonald, Aron Baksh, Alexandria Holland, Heewhan Shin, Phoebe A. Rice, W. Marshall Stark, Femi J. Olorunniji
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Large serine recombinases
Serine integrase
Site-specific recombination
Alphafold multimer.
Online Access:https://doi.org/10.1038/s41598-024-77570-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-024-77570-9

Similar Items