Isolation, characterization, and vascular potential of porcine cells in a three-dimensional decellularized liver matrix model

Isolation, characterization, and vascular potential of porcine cells in a three-dimensional decellularized liver matrix model

IntroductionThe bioengineering of solid tissues and organs to mitigate the organ donor shortage has become a critical area of research in tissue engineering and regenerative medicine, where establishing a functional vascular network is crucial, particularly for complex organs such as the lung, kidne...

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Main Authors: Sara Morini, Sandra Melitón Barbancho, Álvaro Blanes Rodríguez, Iris Pla-Palacín, Pilar Sainz-Arnal, Natalia Sánchez-Romero, Maria Victoria Falceto, Olga Mitjana, Antonio Romero, Marcela Del Rio-Nechaevsky, Maria Lourdes Bengochea Martinez, Emma Olmedo Arbizu, Sara Lorente, Angel Lanas, Ana Fernandes-Platzgummer, Pedro M. Baptista
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stromal cells
smooth muscle cells
endothelial cells
decellularized liver ECM
3D dECM disc vascular model
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1625999/full
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https://www.frontiersin.org/articles/10.3389/fbioe.2025.1625999/full

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