Synthesis and biological activity of arylheteraaliphatic amino amides

Synthesis and biological activity of arylheteraaliphatic amino amides

The synthesis of a series of N-substituted arylheteraaliphatic amino amides was carried out to determine their antiarrhythmic activity. Styrene oxide was the initial compound for the synthesis. Its oxirane ring was opened with N,N-dialkylaminoethanols in the presence of alcoholates. It was found tha...

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Bibliographic Details
Main Authors: А. I. Ivanova, Е. Ya. Borisova, N. Yu. Borisova, D. Q. Hoang, Е. V. Arzamastsev
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2015-02-01
Series:Тонкие химические технологии
Subjects:
2-[2-(dialkylamino)ethoxy]-1-phenylethanols, n-{2-[2-(dialkylamino)ethoxy]-1- phenylethyl}benzamides, the krasusky rule, the ritter reaction, antiarrhythmic activity
Online Access:https://www.finechem-mirea.ru/jour/article/view/216
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