Protocol for assessing the clogging of the mitochondrial translocase of the outer membrane by precursor proteins in human cells

Summary: Protein import into the mitochondria is required for organellar function. Inefficient import can result in the stalling of mitochondrial precursors inside the translocase of the outer membrane (TOM) and blockage of the mitochondrial entry gate. Here, we present a protocol to assess the clog...

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Bibliographic Details
Main Authors: John Kim, Hilla Weidberg
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725000231
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