Distinct network patterns emerge from Cartesian and XOR epistasis models: a comparative network science analysis

Distinct network patterns emerge from Cartesian and XOR epistasis models: a comparative network science analysis

Abstract Background Epistasis, the phenomenon where the effect of one gene (or variant) is masked or modified by one or more other genes, significantly contributes to the phenotypic variance of complex traits. Traditionally, epistasis has been modeled using the Cartesian epistatic model, a multiplic...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhendong Sha, Philip J. Freda, Priyanka Bhandary, Attri Ghosh, Nicholas Matsumoto, Jason H. Moore, Ting Hu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BioData Mining
Subjects:
Epistasis
Interaction model
XOR
Network science
Network analysis
Higher-order interactions
Online Access:https://doi.org/10.1186/s13040-024-00413-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13040-024-00413-w

Similar Items