Pirfenidone combined with UC-MSCs reversed bleomycin-induced pulmonary fibrosis

Abstract Pulmonary fibrosis (PF) is a progressive, irreversible disease with limited effective treatments. Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) have recently shown promise in PF therapy. This study evaluated the therapeutic effects and mechanisms of UC-MSCs combined with pir...

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Bibliographic Details
Main Authors: Jingran Xu, Zulipikaer Abudureheman, Hui Gong, Xuemei Zhong, Lexin Xue, Xiaoguang Zou, Li Li
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-14286-4
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