Investigation of the anti-influenza activity of siRNA complexes against the cellular genes <i>FLT4, Nup98</i>, and <i>Nup205 in vitro</i>

Investigation of the anti-influenza activity of siRNA complexes against the cellular genes <i>FLT4, Nup98</i>, and <i>Nup205 in vitro</i>

Objectives. Evaluation of changes in the viral activity of influenza A/WSN/33 after complex knockdown of combinations of cellular genes FLT4, Nup98 and Nup205 in human lung cell culture A549. Methods. The work was carried out using the equipment of the Center for Collective Use of the I. Mechnikov R...

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Main Authors: E. A. Pashkov, M. O. Korotysheva, A. V. Pak, E. B. Faizuloev, A. V. Sidorov, A. V. Poddubikov, E. P. Bystritskaya, Yu. E. Dronina, V. K. Solntseva, T. A. Zaiceva, E. P. Pashkov, A. S. Bykov, O. A. Svitich, V. V. Zverev
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2022-06-01
Series:Тонкие химические технологии
Subjects:
rna interference
influenza a virus
gene expression
mrna
small interfering rna
viral rna
Online Access:https://www.finechem-mirea.ru/jour/article/view/1822
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