TRC120038, a Novel Dual AT1/ETA Receptor Blocker for Control of Hypertension, Diabetic Nephropathy, and Cardiomyopathy in ob-ZSF1 Rats

In hypertensive subjects, angiotensin II and endothelin participate in a manner involving closely interwoven pathways in increasing blood pressure (BP) and inducing end organ damage. The primary objective of this study was to determine the effect of TRC120038, a novel dual AT1/ETA receptor blocker o...

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Bibliographic Details
Main Authors: Anookh Mohanan, Ram Gupta, Amita Dubey, Vikrant Jagtap, Appaji Mandhare, Ramesh C. Gupta, Vijay Chauthaiwale, Chaitanya Dutt
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.4061/2011/751513
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