MaxComp: Predicting single-cell chromatin compartments from 3D chromosome structures.

The genome is organized into distinct chromatin compartments with at least two main classes, a transcriptionally active A and an inactive B compartment, broadly corresponding to euchromatin and heterochromatin. Chromatin regions within the same compartment preferentially interact with each other ove...

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Bibliographic Details
Main Authors: Yuxiang Zhan, Francesco Musella, Frank Alber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013114
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