Antifungal Activity and Cytotoxicity of Imidazole- and Morpholine-Based Lysosomotropic Detergents

Antifungal Activity and Cytotoxicity of Imidazole- and Morpholine-Based Lysosomotropic Detergents

Background. The spread of infectious diseases caused by drug-resistant bacteria and fungi, especially nosoco­mial strains, is currently considered a serious medical problem. It is known that the fungus Candida albicans is the most common causative agent of candidal infection, including the severe t...

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Bibliographic Details
Main Authors: Diana Hodyna, Vasyl Kovalishyn, Yurii Shulha, Olena Trokhimenko, Olesya Aksenovska, Sergiy Rogalsky, Larysa Metelytsia
Format: Article
Language:English
Published: Igor Sikorsky Kyiv Polytechnic Institute 2025-03-01
Series:Innovative Biosystems and Bioengineering
Subjects:
lysosomotropic detergents
1-alkylimidazole
N-alkylmorpholine
anti-Candida activity
cytotoxicity
molecular docking
Online Access:https://ibb.kpi.ua/article/view/315523
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https://ibb.kpi.ua/article/view/315523

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