Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel release

Purpose: To compare anesthesia techniques (WALANT (wide-awake anesthesia no tourniquet), locoregional anesthesia, local anesthesia with tourniquet or sedation) for carpal tunnel release (CTR). Methods: A comprehensive literature search was conducted on PubMed, MEDLINE, Embase and the Cochrane Librar...

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Main Authors: Laurentiu-Cosmin Focsa, Pierre-Alban Bouché, Thomas Apard, Daphné Querel, Marc-Antoine Rousseau, Jules Descamps
Format: Article
Language:English
Published: Bioscientifica 2025-01-01
Series:EFORT Open Reviews
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Online Access:https://eor.bioscientifica.com/view/journals/eor/10/1/EOR-2024-0014.xml
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author Laurentiu-Cosmin Focsa
Pierre-Alban Bouché
Thomas Apard
Daphné Querel
Marc-Antoine Rousseau
Jules Descamps
author_facet Laurentiu-Cosmin Focsa
Pierre-Alban Bouché
Thomas Apard
Daphné Querel
Marc-Antoine Rousseau
Jules Descamps
author_sort Laurentiu-Cosmin Focsa
collection DOAJ
description Purpose: To compare anesthesia techniques (WALANT (wide-awake anesthesia no tourniquet), locoregional anesthesia, local anesthesia with tourniquet or sedation) for carpal tunnel release (CTR). Methods: A comprehensive literature search was conducted on PubMed, MEDLINE, Embase and the Cochrane Library up to May 2023. Two independent reviewers selected the studies and extracted the data. The primary outcomes included the pain experienced at the moment of anesthesia and during the surgery and the mean morphine equivalents (MME) administered following the surgery and overall patient satisfaction. Our secondary outcomes consisted of the mean room occupancy time and the mean duration of the procedure, followed by the complication rate. The review process was conducted according to PRISMA guidelines. Results: A total of 3166 studies were identified, which included 23 studies comparing various anesthesia types and 28,748 CTR surgeries. The WALANT group experienced significantly lower pain levels during anesthesia (−2.67 (95% CIs: 0.12–4.99)) and surgery (−2.04 (95% CIs: 0.08–4.07)) compared to the local anesthesia group. There was no difference in the use of MME for pain relief among different anesthesia techniques. Satisfaction rates were comparable, but WALANT exhibited the highest probability for utmost satisfaction. The mean room occupancy time was lower in patients receiving local anesthesia compared with when sedation was added, with a mean difference of −27.16 (95% CIs: −52.03 to −1.85). Conclusions: The WALANT technique for CTR reported better outcomes for pain (during anesthesia and surgery), higher satisfaction and low probability to expand the operating room occupancy time. Level of evidence: Level II of evidence.
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spelling doaj-art-73360c5fb7a743928b0eb0c075bc4d562025-01-07T17:19:14ZengBioscientificaEFORT Open Reviews2058-52412025-01-0110131310.1530/EOR-2024-00141Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel releaseLaurentiu-Cosmin Focsa0Pierre-Alban Bouché1Thomas Apard2Daphné Querel3Marc-Antoine Rousseau4Jules Descamps5Department of Orthopedics and Trauma Surgery at Bichat-Beaujon Hospitals, APHP, Paris, FranceDepartment of Orthopedics and Trauma Surgery at Lariboisière Hospital, APHP, Paris, FranceCentre d’échochirurgie, Versailles, FranceDepartment of Orthopedics and Trauma Surgery at Lariboisière Hospital, APHP, Paris, FranceDepartment of Orthopedics and Trauma Surgery at Bichat-Beaujon Hospitals, APHP, Paris, FranceDepartment of Orthopedics and Trauma Surgery at Lariboisière Hospital, APHP, Paris, FrancePurpose: To compare anesthesia techniques (WALANT (wide-awake anesthesia no tourniquet), locoregional anesthesia, local anesthesia with tourniquet or sedation) for carpal tunnel release (CTR). Methods: A comprehensive literature search was conducted on PubMed, MEDLINE, Embase and the Cochrane Library up to May 2023. Two independent reviewers selected the studies and extracted the data. The primary outcomes included the pain experienced at the moment of anesthesia and during the surgery and the mean morphine equivalents (MME) administered following the surgery and overall patient satisfaction. Our secondary outcomes consisted of the mean room occupancy time and the mean duration of the procedure, followed by the complication rate. The review process was conducted according to PRISMA guidelines. Results: A total of 3166 studies were identified, which included 23 studies comparing various anesthesia types and 28,748 CTR surgeries. The WALANT group experienced significantly lower pain levels during anesthesia (−2.67 (95% CIs: 0.12–4.99)) and surgery (−2.04 (95% CIs: 0.08–4.07)) compared to the local anesthesia group. There was no difference in the use of MME for pain relief among different anesthesia techniques. Satisfaction rates were comparable, but WALANT exhibited the highest probability for utmost satisfaction. The mean room occupancy time was lower in patients receiving local anesthesia compared with when sedation was added, with a mean difference of −27.16 (95% CIs: −52.03 to −1.85). Conclusions: The WALANT technique for CTR reported better outcomes for pain (during anesthesia and surgery), higher satisfaction and low probability to expand the operating room occupancy time. Level of evidence: Level II of evidence.https://eor.bioscientifica.com/view/journals/eor/10/1/EOR-2024-0014.xmlcarpal tunnel syndromewalantnetwork meta-analysislocal anesthesia
spellingShingle Laurentiu-Cosmin Focsa
Pierre-Alban Bouché
Thomas Apard
Daphné Querel
Marc-Antoine Rousseau
Jules Descamps
Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel release
EFORT Open Reviews
carpal tunnel syndrome
walant
network meta-analysis
local anesthesia
title Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel release
title_full Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel release
title_fullStr Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel release
title_full_unstemmed Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel release
title_short Network meta-analysis comparing WALANT, locoregional, local and general anesthesia techniques in carpal tunnel release
title_sort network meta analysis comparing walant locoregional local and general anesthesia techniques in carpal tunnel release
topic carpal tunnel syndrome
walant
network meta-analysis
local anesthesia
url https://eor.bioscientifica.com/view/journals/eor/10/1/EOR-2024-0014.xml
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