Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention

Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention

In recent years, the near-infrared (NIR) fluorescence theranostic system has garnered increasing attention for its advantages in the simultaneous diagnosis- and imaging-guided delivery of therapeutic drugs. However, challenges such as strong background fluorescence signals and rapid metabolism have...

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Bibliographic Details
Main Authors: Xiaohua Wang, Xiaofei Deng, Lilan Xin, Chune Dong, Guoyuan Hu, Hai-Bing Zhou
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
estrogen receptors
drug delivery
NIR fluorescence imaging
prodrug conjugates
pegylation
esterase activation
Online Access:https://www.mdpi.com/1420-3049/30/2/305
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