Long-term kinetics of proviral load in HTLV-1 carriers: defining risk for the development of adult T-cell leukemia/lymphoma

Long-term kinetics of proviral load in HTLV-1 carriers: defining risk for the development of adult T-cell leukemia/lymphoma

Abstract Background Assessment of adult T-cell leukemia/lymphoma (ATL) development among human T-lymphotropic virus 1 (HTLV-1)-infected individuals (carriers) constitute a significant issue. A high HTLV-1 proviral load (PVL) in carriers has been used as a risk factor for ATL development and PVLs are...

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Bibliographic Details
Main Authors: Koji Jimbo, Masanori Nojima, Keiko Toriuchi, Makoto Yamagishi, Makoto Nakashima, Yoshihisa Yamano, Kaoru Uchimaru, Yasuhito Nannya
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Biomarker Research
Subjects:
Human T-lymphotropic virus 1 (HTLV-1)
Adult T-cell leukemia/lymphoma (ATL)
Proviral load
Trajectory analysis
Risk estimation
Online Access:https://doi.org/10.1186/s40364-025-00747-5
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https://doi.org/10.1186/s40364-025-00747-5

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