Daptomycin forms a stable complex with phosphatidylglycerol for selective uptake to bacterial membrane

Daptomycin is a potent lipopeptide antibiotic used in the treatment of life-threatening Gram-positive infections, but the molecular mechanism of its interaction with bacterial membrane remains unclear. Here, we show that this interaction is divided into two stages, of which the first is a fast and r...

Full description

Saved in:
Bibliographic Details
Main Authors: Pragyansree Machhua, Vignesh Gopalakrishnan Unnithan, Yu Liu, Yiping Jiang, Lingfeng Zhang, Zhihong Guo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/93267
Tags: Add Tag
No Tags, Be the first to tag this record!