Diagnostic Stratification of Prostate Cancer Through Blood-Based Biochemical and Inflammatory Markers

Diagnostic Stratification of Prostate Cancer Through Blood-Based Biochemical and Inflammatory Markers

<b>Background:</b> Prostate cancer (PCa) remains one of the most prevalent malignancies in men, with diagnostic challenges arising from the limited specificity of current biomarkers, like PSA. Improved stratification tools are essential to reduce overdiagnosis and guide personalized pati...

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Main Authors: Donatella Coradduzza, Leonardo Sibono, Alessandro Tedde, Sonia Marra, Maria Rosaria De Miglio, Angelo Zinellu, Serenella Medici, Arduino A. Mangoni, Massimiliano Grosso, Massimo Madonia, Ciriaco Carru
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diagnostics
Subjects:
biomarker discovery
prostate cancer
multivariate analysis
adaptive Box–Cox transformation
LASSO regression
probabilistic principal component analysis (PPCA)
Online Access:https://www.mdpi.com/2075-4418/15/11/1385
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