A genome‐scale screen reveals context‐dependent ovarian cancer sensitivity to miRNA overexpression

A genome‐scale screen reveals context‐dependent ovarian cancer sensitivity to miRNA overexpression

Abstract Large‐scale molecular annotation of epithelial ovarian cancer (EOC) indicates remarkable heterogeneity in the etiology of that disease. This diversity presents a significant obstacle against intervention target discovery. However, inactivation of miRNA biogenesis is commonly associated with...

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Bibliographic Details
Main Authors: Benjamin B Shields, Chad V Pecot, Hua Gao, Elizabeth McMillan, Malia Potts, Christa Nagel, Scott Purinton, Ying Wang, Cristina Ivan, Hyun Seok Kim, Robert J Borkowski, Shaheen Khan, Cristian Rodriguez‐Aguayo, Gabriel Lopez‐Berestein, Jayanthi Lea, Adi Gazdar, Keith A Baggerly, Anil K Sood, Michael A White
Format: Article
Language:English
Published: Springer Nature 2015-12-01
Series:Molecular Systems Biology
Subjects:
cancer
cancer genetics
microRNA
miRNA
ovarian cancer
Online Access:https://doi.org/10.15252/msb.20156308
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https://doi.org/10.15252/msb.20156308

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