The novel house dust mite allergen Der p 39 exacerbates atopic dermatitis-like inflammation in mice by inducing skin barrier dysfunction

The novel house dust mite allergen Der p 39 exacerbates atopic dermatitis-like inflammation in mice by inducing skin barrier dysfunction

Background: House dust mite (HDM) allergens can induce or exacerbate allergic inflammation, including atopic dermatitis (AD). Substances that damage the epithelial barrier can trigger or worsen AD. The mechanism by which the novel HDM allergen Der p 39 induces allergic inflammation remains unclear....

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Bibliographic Details
Main Authors: Shan Liu, BSc, Ze-Lang Cai, MS, Jingcheng Liu, Si-Yi Que, BSc, Wan-Zhen Hu, MS, Liang Chen, MS, Jia-Jie Chen, PhD, Kunmei Ji, PhD
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:World Allergy Organization Journal
Subjects:
House dust mite
Der p 39
Skin barrier
Atopic dermatitis
Skin inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455125000110
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