Alzheimer’s Disease: In Vitro and In Vivo Evidence of Activation of the Plasma Bradykinin-Forming Cascade and Implications for Therapy

The plaques associated with Alzheimer’s disease are formed as a result of the aggregation of Aβ peptides, which vary in length from 38 to 43 amino acids. The 1-40 peptide is the most abundant, while the 1-42 peptide appears to be the most destructive to neurons and/or glial cells in a variety of ass...

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Bibliographic Details
Main Authors: Allen P. Kaplan, Berhane Ghebrehiwet, Kusumam Joseph
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/24/2039
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