Hyperhomocysteinemia in Takayasu arteritis—genetically defined or burden of the proinflammatory state?

Hyperhomocysteinemia in Takayasu arteritis—genetically defined or burden of the proinflammatory state?

Takayasu arteritis (TAK) is associated with high plasma homocysteine (Hcy) and elevated Hcy predicts ischemic events. Thus, this study aims to compare the frequency of single-nucleotide polymorphisms (SNPs) of genes involved in Hcy metabolism between TAK and controls and analyze associations with Hc...

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Main Authors: Eduarda Bonelli Zarur, Faustino Peron Filho, Allan Chiaratti de Oliveira, Gerson Dierley Keppeke, Vânia D’Almeida, Alexandre Wagner Silva de Souza
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
Takayasu Arteritis
hyperhomocysteinemia
cardiovascular disease
arterial inflammation
single nucleotide polymorphism
homocysteine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574479/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574479/full

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