Risk profiling for cirrhosis and hepatocellular carcinoma in HFE hemochromatosis using mobilizable iron stores and alcohol consumption
Abstract HFE hemochromatosis (HH) may cause cirrhosis and hepatocellular carcinoma (HCC). Progression to these endpoints depends on the severity of iron overload and cofactors, such as alcohol. We evaluated alcohol and iron-related risk factors in relation to cirrhosis at diagnosis and future develo...
Saved in:
| Main Authors: | Natasha D. P. Mitchell, Timothy G. St Pierre, Louise E. Ramm, Grant A. Ramm, John K. Olynyk |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-99672-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Chronic hepatitis B in children carried out of the hemochromatosis gene HFE
by: F. I. Inoyatova, et al.
Published: (2021-07-01) -
HFE-Related Hemochromatosis May Be a Primary Kupffer Cell Disease
by: Elias Kouroumalis, et al.
Published: (2025-03-01) -
HFE mutations in patients with iron overload in Santa Catarina: a cross-sectional study
by: Cristiane Manfé Pagliosa, et al.
Published: (2025-07-01) -
Hereditary hemochromatosis: pathogenesis, symptoms, diagnosis and current treatment - literature review
by: Dominika Prystacka-Szar, et al.
Published: (2025-04-01) -
Factors related to mean corpuscular volume in HFE p.C282Y homozygotes
by: James C. Barton, et al.
Published: (2025-02-01)